Rosiglitazone Attenuates Chronic Hypoxia–Induced Pulmonary Hypertension in a Mouse Model

Chronic hypoxia contributes to pulmonary hypertension through complex mechanisms that include enhanced NADPH oxidase expression and reactive oxygen species (ROS) generation in the lung. Stimulation of peroxisome proliferator–activated receptor γ (PPARγ) reduces the expression and activity of NADPH o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Nisbet, Rachel E., Bland, Jennifer M., Kleinhenz, Dean J., Mitchell, Patrick O., Walp, Erik R., Sutliff, Roy L., Hart, C. Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2010
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848739/
https://ncbi.nlm.nih.gov/pubmed/19520921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0132OC
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge