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Rosiglitazone Attenuates Chronic Hypoxia–Induced Pulmonary Hypertension in a Mouse Model
Chronic hypoxia contributes to pulmonary hypertension through complex mechanisms that include enhanced NADPH oxidase expression and reactive oxygen species (ROS) generation in the lung. Stimulation of peroxisome proliferator–activated receptor γ (PPARγ) reduces the expression and activity of NADPH o...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Thoracic Society
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848739/ https://ncbi.nlm.nih.gov/pubmed/19520921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0132OC |
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