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HIF-1α-Mediated, NADPH Oxidase-Derived ROS Contributes to Laryngeal Airway Hyperreactivity Induced by Intermittent Hypoxia in Rats

Obstructive sleep apnea, similar to intermittent hypoxia (IH) during sleep, is associated with laryngeal airway hyperreactivity (LAH). IH-induced laryngeal oxidative stress may contribute to LAH, but the underlying mechanism remains unknown. Conscious rats were subjected to repetitive 75 s cycles of...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Lin, You Shuei, Shen, Yan-Jhih, Ou, Ping-Hsun, Lai, Ching Jung
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575773/
https://ncbi.nlm.nih.gov/pubmed/33117193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.575260
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