NADPH Oxidase-Derived ROS Induced by Chronic Intermittent Hypoxia Mediates Hypersensitivity of Lung Vagal C Fibers in Rats

Obstructive sleep apnea (OSA), manifested by exposure to chronic intermittent hypoxia (CIH) and excess production of reactive oxygen species (ROS) in the airways, is associated with hyperreactive airway diseases. ROS, particularly when created by NADPH oxidase, are known to sensitize lung vagal C fi...

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Publicat a:Front Physiol
Autors principals: Yang, Chang-Huan, Zhuang, Wei-Ling, Shen, Yan-Jhih, Lai, Ching Jung, Kou, Yu Ru
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860401/
https://ncbi.nlm.nih.gov/pubmed/27242540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00166
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