NADPH Oxidase-Derived ROS Induced by Chronic Intermittent Hypoxia Mediates Hypersensitivity of Lung Vagal C Fibers in Rats

Obstructive sleep apnea (OSA), manifested by exposure to chronic intermittent hypoxia (CIH) and excess production of reactive oxygen species (ROS) in the airways, is associated with hyperreactive airway diseases. ROS, particularly when created by NADPH oxidase, are known to sensitize lung vagal C fi...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Yang, Chang-Huan, Zhuang, Wei-Ling, Shen, Yan-Jhih, Lai, Ching Jung, Kou, Yu Ru
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860401/
https://ncbi.nlm.nih.gov/pubmed/27242540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00166
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