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SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins

Emerging evidence supports roles for secreted extracellular matrix proteins in boosting synaptogenesis, synaptic transmission, and synaptic plasticity. SPARCL1 (also known as Hevin), a secreted non-neuronal protein, was reported to increase synaptogenesis by simultaneously binding to presynaptic neu...

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Библиографические подробности
Опубликовано в: :J Neurosci
Главные авторы: Gan, Kathlyn J., Südhof, Thomas C.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574652/
https://ncbi.nlm.nih.gov/pubmed/32973045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0454-20.2020
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