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Activity-Dependent Validation of Excitatory vs. Inhibitory Synapses by Neuroligin-1 vs. Neuroligin-2
Neuroligins enhance synapse formation in vitro, but surprisingly are not required for the generation of synapses in vivo. We now show that in cultured neurons, neuroligin-1 overexpression increases excitatory but not inhibitory synaptic responses, and potentiates synaptic NMDA/AMPA-receptor ratios....
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738748/ https://ncbi.nlm.nih.gov/pubmed/17582332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.05.029 |
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