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A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin

Factors that control differentiation of presynaptic and postsynaptic elements into excitatory or inhibitory synapses are poorly defined. Here we show that the postsynaptic density (PSD) proteins PSD-95 and neuroligin-1 (NLG) are critical for dictating the ratio of excitatory-to-inhibitory synaptic c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prange, Oliver, Wong, Tak Pan, Gerrow, Kimberly, Wang, Yu Tian, El-Husseini, Alaa
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC518853/
https://ncbi.nlm.nih.gov/pubmed/15358863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405939101
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