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Pin1 Binding to Phosphorylated PSD-95 Regulates the Number of Functional Excitatory Synapses
The post-synaptic density protein 95 (PSD-95) plays a central role in excitatory synapse development and synaptic plasticity. Phosphorylation of the N-terminus of PSD-95 at threonine 19 (T19) and serine 25 (S25) decreases PSD-95 stability at synapses; however, a molecular mechanism linking PSD-95 ph...
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| Publicado en: | Front Mol Neurosci |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082786/ https://ncbi.nlm.nih.gov/pubmed/32231520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00010 |
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