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Pin1 Binding to Phosphorylated PSD-95 Regulates the Number of Functional Excitatory Synapses
The post-synaptic density protein 95 (PSD-95) plays a central role in excitatory synapse development and synaptic plasticity. Phosphorylation of the N-terminus of PSD-95 at threonine 19 (T19) and serine 25 (S25) decreases PSD-95 stability at synapses; however, a molecular mechanism linking PSD-95 ph...
Gorde:
| Argitaratua izan da: | Front Mol Neurosci |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Frontiers Media S.A.
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082786/ https://ncbi.nlm.nih.gov/pubmed/32231520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00010 |
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