Activity-Dependent Validation of Excitatory vs. Inhibitory Synapses by Neuroligin-1 vs. Neuroligin-2

Neuroligins enhance synapse formation in vitro, but surprisingly are not required for the generation of synapses in vivo. We now show that in cultured neurons, neuroligin-1 overexpression increases excitatory but not inhibitory synaptic responses, and potentiates synaptic NMDA/AMPA-receptor ratios....

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Detaylı Bibliyografya
Asıl Yazarlar: Chubykin, Alexander A., Atasoy, Deniz, Etherton, Mark R., Brose, Nils, Kavalali, Ege T., Gibson, Jay R., Südhof, Thomas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738748/
https://ncbi.nlm.nih.gov/pubmed/17582332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.05.029
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