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SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins

Emerging evidence supports roles for secreted extracellular matrix proteins in boosting synaptogenesis, synaptic transmission, and synaptic plasticity. SPARCL1 (also known as Hevin), a secreted non-neuronal protein, was reported to increase synaptogenesis by simultaneously binding to presynaptic neu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gan, Kathlyn J., Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574652/
https://ncbi.nlm.nih.gov/pubmed/32973045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0454-20.2020
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