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LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation

Recently, leucine-rich repeat transmembrane proteins (LRRTMs) were found to be synaptic cell-adhesion molecules that, when expressed in non-neuronal cells, induce presynaptic differentiation in contacting axons. We now demonstrate that LRRTM2 induces only excitatory synapses, and that it also acts i...

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Autori principali: Ko, Jaewon, Fuccillo, Marc V., Malenka, Robert C., Südhof, Thomas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829314/
https://ncbi.nlm.nih.gov/pubmed/20064387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.12.012
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