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LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation
We identify the leucine-rich repeat transmembrane protein LRRTM2 as a key regulator of excitatory synapse development and function. LRRTM2 localizes to excitatory synapses in transfected hippocampal neurons, and shRNA-mediated knockdown of LRRTM2 leads to a decrease in excitatory synapses without af...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829666/ https://ncbi.nlm.nih.gov/pubmed/20064388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.12.019 |
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