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Postsynaptic FLRT proteins are endogenous ligands for the black widow spider venom receptor Latrophilin and regulate excitatory synapse development
Latrophilins (LPHNs) are a small family of G-protein coupled receptors known to mediate the massive synaptic exocytosis caused by the black widow spider venom α-latrotoxin, but their endogenous ligands and function remain unclear. Mutations in LPHN3 are strongly associated with attention deficit hyp...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326387/ https://ncbi.nlm.nih.gov/pubmed/22405201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.01.018 |
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