The Oncometabolite 5′-Deoxy-5′-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation

Tumor cells develop various mechanisms to escape immune surveillance. In this context, oncometabolites secreted by tumor cells due to deregulated metabolic pathways, have been in the spotlight of researchers during the last years. 5′-Deoxy-5′-methylthioadenosine (MTA) phosphorylase (MTAP) deficiency...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Jacobs, Benedikt, Schlögl, Sebastian, Strobl, Carolin Dorothea, Völkl, Simon, Stoll, Andrej, Mougiakakos, Dimitrios, Malmberg, Karl-Johan, Mackensen, Andreas, Aigner, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573074/
https://ncbi.nlm.nih.gov/pubmed/33123121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02128
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