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Protease Inhibition Mechanism of Camelid-like Synthetic Human Antibodies

Macromolecular protease inhibitors and camelid single-domain antibodies achieve their enzymic inhibition functions often through protruded structures that directly interact with catalytic centers of targeted proteases. Inspired by this phenomenon, we constructed synthetic human antibody libraries en...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Nam, Dong Hyun, Lee, Ki Baek, Kruchowy, Evan, Pham, Henry, Ge, Xin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572768/
https://ncbi.nlm.nih.gov/pubmed/32997500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00690
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