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Efficient Antibody Assembly in E. coli Periplasm by Disulfide Bond Folding Factor Co-expression and Culture Optimization

Molecular chaperones and protein folding factors of bacterial periplasmic space play important roles in assisting disulfide bond formation and proper protein folding. In this study, effects of disulfide bond protein (Dsb) families were investigated on assembly of 3F3 Fab, an antibody inhibitor targe...

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Detaylı Bibliyografya
Yayımlandı:Appl Biochem Biotechnol
Asıl Yazarlar: Rodriguez, Carlos, Nam, Dong Hyun, Kruchowy, Evan, Ge, Xin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898612/
https://ncbi.nlm.nih.gov/pubmed/28488120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12010-017-2502-8
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