Functional selection of protease inhibitory antibodies

Critical for diverse biological processes, proteases represent one of the largest families of pharmaceutical targets. To inhibit pathogenic proteases with desired selectivity, monoclonal antibodies (mAbs) hold great promise as research tools and therapeutic agents. However, identification of mAbs wi...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Lopez, Tyler, Mustafa, Zahid, Chen, Chuan, Lee, Ki Baek, Ramirez, Aaron, Benitez, Chris, Luo, Xin, Ji, Ru-Rong, Ge, Xin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697876/
https://ncbi.nlm.nih.gov/pubmed/31363054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903330116
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