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Functional selection of protease inhibitory antibodies

Critical for diverse biological processes, proteases represent one of the largest families of pharmaceutical targets. To inhibit pathogenic proteases with desired selectivity, monoclonal antibodies (mAbs) hold great promise as research tools and therapeutic agents. However, identification of mAbs wi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lopez, Tyler, Mustafa, Zahid, Chen, Chuan, Lee, Ki Baek, Ramirez, Aaron, Benitez, Chris, Luo, Xin, Ji, Ru-Rong, Ge, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697876/
https://ncbi.nlm.nih.gov/pubmed/31363054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903330116
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