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Functional selection of protease inhibitory antibodies

Critical for diverse biological processes, proteases represent one of the largest families of pharmaceutical targets. To inhibit pathogenic proteases with desired selectivity, monoclonal antibodies (mAbs) hold great promise as research tools and therapeutic agents. However, identification of mAbs wi...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lopez, Tyler, Mustafa, Zahid, Chen, Chuan, Lee, Ki Baek, Ramirez, Aaron, Benitez, Chris, Luo, Xin, Ji, Ru-Rong, Ge, Xin
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697876/
https://ncbi.nlm.nih.gov/pubmed/31363054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903330116
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