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Pan-cancer Analysis of CDK12 Alterations Identifies a Subset of Prostate Cancers with Distinct Genomic and Clinical Characteristics

BACKGROUND: CDK12 genomic alterations occur in several tumor types, but little is known about their oncogenic role and clinical significance. OBJECTIVE: To describe the landscape of CDK12 alterations across solid cancers and the clinical features of CDK12-altered prostate cancer. DESIGN, SETTING, AN...

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Bibliografiska uppgifter
I publikationen:Eur Urol
Huvudupphovsmän: Nguyen, Bastien, Mota, Jose Mauricio, Nandakumar, Subhiksha, Stopsack, Konrad H., Weg, Emily, Rathkopf, Dana, Morris, Michael J., Scher, Howard I., Kantoff, Philip W., Gopalan, Anuradha, Zamarin, Dmitriy, Solit, David B., Schultz, Nikolaus, Abida, Wassim
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572747/
https://ncbi.nlm.nih.gov/pubmed/32317181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2020.03.024
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