Pan-cancer Analysis of CDK12 Alterations Identifies a Subset of Prostate Cancers with Distinct Genomic and Clinical Characteristics

BACKGROUND: CDK12 genomic alterations occur in several tumor types, but little is known about their oncogenic role and clinical significance. OBJECTIVE: To describe the landscape of CDK12 alterations across solid cancers and the clinical features of CDK12-altered prostate cancer. DESIGN, SETTING, AN...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Eur Urol
Hlavní autoři: Nguyen, Bastien, Mota, Jose Mauricio, Nandakumar, Subhiksha, Stopsack, Konrad H., Weg, Emily, Rathkopf, Dana, Morris, Michael J., Scher, Howard I., Kantoff, Philip W., Gopalan, Anuradha, Zamarin, Dmitriy, Solit, David B., Schultz, Nikolaus, Abida, Wassim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572747/
https://ncbi.nlm.nih.gov/pubmed/32317181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2020.03.024
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky