Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

The level of copy number alteration (CNA), termed CNA burden, in the tumor genome is associated with recurrence of primary prostate cancer. Whether CNA burden is associated with prostate cancer survival or outcomes in other cancers is unknown. We analyzed the CNA landscape of conservatively treated...

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Foilsithe in:eLife
Main Authors: Hieronymus, Haley, Murali, Rajmohan, Tin, Amy, Yadav, Kamlesh, Abida, Wassim, Moller, Henrik, Berney, Daniel, Scher, Howard, Carver, Brett, Scardino, Peter, Schultz, Nikolaus, Taylor, Barry, Vickers, Andrew, Cuzick, Jack, Sawyers, Charles L
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2018
Ábhair:
Cancer Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145837/
https://ncbi.nlm.nih.gov/pubmed/30178746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37294
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