Platinum-Based Chemotherapy in Metastatic Prostate Cancer With DNA Repair Gene Alterations

PURPOSE: Alterations in DNA damage repair (DDR) genes occur in up to 25% of patients with metastatic castration-resistant prostate cancer (mCRPC) and may sensitize to platinum chemotherapy. We aimed to evaluate the efficacy of platinum-based chemotherapy in DDR-mutant (DDRmut) mCRPC. METHODS: We ass...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:JCO Precis Oncol
Main Authors: Mota, Jose Mauricio, Barnett, Ethan, Nauseef, Jones T., Nguyen, Bastien, Stopsack, Konrad H., Wibmer, Andreas, Flynn, Jessica R., Heller, Glenn, Danila, Daniel C., Rathkopf, Dana, Slovin, Susan, Kantoff, Philip W., Scher, Howard I., Morris, Michael J., Schultz, Nikolaus, Solit, David B., Abida, Wassim
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Clinical Oncology 2020
Assuntos:
Original Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446522/
https://ncbi.nlm.nih.gov/pubmed/32856010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00346
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares