Platinum-Based Chemotherapy in Metastatic Prostate Cancer With DNA Repair Gene Alterations

PURPOSE: Alterations in DNA damage repair (DDR) genes occur in up to 25% of patients with metastatic castration-resistant prostate cancer (mCRPC) and may sensitize to platinum chemotherapy. We aimed to evaluate the efficacy of platinum-based chemotherapy in DDR-mutant (DDRmut) mCRPC. METHODS: We ass...

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Detaylı Bibliyografya
Yayımlandı:JCO Precis Oncol
Asıl Yazarlar: Mota, Jose Mauricio, Barnett, Ethan, Nauseef, Jones T., Nguyen, Bastien, Stopsack, Konrad H., Wibmer, Andreas, Flynn, Jessica R., Heller, Glenn, Danila, Daniel C., Rathkopf, Dana, Slovin, Susan, Kantoff, Philip W., Scher, Howard I., Morris, Michael J., Schultz, Nikolaus, Solit, David B., Abida, Wassim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Clinical Oncology 2020
Konular:
Original Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446522/
https://ncbi.nlm.nih.gov/pubmed/32856010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00346
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