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Targeting an autocrine IL-6 – SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma

A major clinical challenge of ovarian cancer is the development of malignant ascites accompanied by widespread peritoneal metastasis. In ovarian clear cell carcinoma (OCCC), a challenging subtype of ovarian cancer, this problem is compounded by near-universal primary chemoresistance; patients with a...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Mehner, Christine, Miller, Erin, Hockla, Alexandra, Coban, Mathew, Weroha, S. John, Radisky, Derek C., Radisky, Evette S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572712/
https://ncbi.nlm.nih.gov/pubmed/32929152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01451-4
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