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PRSS3/Mesotrypsin is a therapeutic target for metastatic prostate cancer

PRSS3/mesotrypsin is an atypical isoform of trypsin that has been associated with breast, lung, and pancreatic cancer cell malignancy. In analyses of open source transcriptional microarray data, we find that PRSS3 expression is upregulated in metastatic prostate cancer tissue, and that expression of...

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Bibliografiske detaljer
Main Authors: Hockla, Alexandra, Miller, Erin, Salameh, Moh’d A., Copland, John A., Radisky, Derek C., Radisky, Evette S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531873/
https://ncbi.nlm.nih.gov/pubmed/23258495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0314
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