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PRSS3/Mesotrypsin is a therapeutic target for metastatic prostate cancer

PRSS3/mesotrypsin is an atypical isoform of trypsin that has been associated with breast, lung, and pancreatic cancer cell malignancy. In analyses of open source transcriptional microarray data, we find that PRSS3 expression is upregulated in metastatic prostate cancer tissue, and that expression of...

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Detalles Bibliográficos
Main Authors: Hockla, Alexandra, Miller, Erin, Salameh, Moh’d A., Copland, John A., Radisky, Derek C., Radisky, Evette S.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531873/
https://ncbi.nlm.nih.gov/pubmed/23258495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0314
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