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PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma

Serine proteases have been implicated as key drivers and facilitators of lung cancer malignancy, and while these proteins represent straightforward targets for therapeutic inhibitors, identification of optimal points for intervention has been complicated by the complex networks in which these enzyme...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Ma, Honghai, Hockla, Alexandra, Mehner, Christine, Coban, Matt, Papo, Niv, Radisky, Derek C., Radisky, Evette S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372636/
https://ncbi.nlm.nih.gov/pubmed/30755669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38362-0
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