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PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma

Serine proteases have been implicated as key drivers and facilitators of lung cancer malignancy, and while these proteins represent straightforward targets for therapeutic inhibitors, identification of optimal points for intervention has been complicated by the complex networks in which these enzyme...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Ma, Honghai, Hockla, Alexandra, Mehner, Christine, Coban, Matt, Papo, Niv, Radisky, Derek C., Radisky, Evette S.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372636/
https://ncbi.nlm.nih.gov/pubmed/30755669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38362-0
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