Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers

Ovarian cancer represents the most lethal tumor type among malignancies of the female reproductive system. Overall survival rates remain low. In this study, we identify the serine protease inhibitor Kazal type 1 (SPINK1) as a potential therapeutic target for a subset of ovarian cancers. We show that...

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Publicado en:Oncotarget
Main Authors: Mehner, Christine, Oberg, Ann L., Kalli, Kimberly R., Nassar, Aziza, Hockla, Alexandra, Pendlebury, Devon, Cichon, Magdalena A., Goergen, Krista M., Maurer, Matthew J., Goode, Ellen L., Keeney, Gary L., Jatoi, Aminah, Sahin-Tóth, Miklós, Copland, John A., Radisky, Derek C., Radisky, Evette S.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742138/
https://ncbi.nlm.nih.gov/pubmed/26437224
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