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Prediction of genome-wide effects of single nucleotide variants on transcription factor binding
Single nucleotide variants (SNVs) located in transcriptional regulatory regions can result in gene expression changes that lead to adaptive or detrimental phenotypic outcomes. Here, we predict gain or loss of binding sites for 741 transcription factors (TFs) across the human genome. We calculated ‘g...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572467/ https://ncbi.nlm.nih.gov/pubmed/33077858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74793-4 |
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