Discovering human transcription factor physical interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays

Identifying transcription factor (TF) binding to noncoding variants, uncharacterized DNA motifs, and repetitive genomic elements has been technically and computationally challenging. Current experimental methods, such as chromatin immunoprecipitation, generally test one TF at a time, and computation...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Shrestha, Shaleen, Sewell, Jared Allan, Santoso, Clarissa Stephanie, Forchielli, Elena, Carrasco Pro, Sebastian, Martinez, Melissa, Fuxman Bass, Juan Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724672/
https://ncbi.nlm.nih.gov/pubmed/31481462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.248823.119
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