Discovering human transcription factor physical interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays

Identifying transcription factor (TF) binding to noncoding variants, uncharacterized DNA motifs, and repetitive genomic elements has been technically and computationally challenging. Current experimental methods, such as chromatin immunoprecipitation, generally test one TF at a time, and computation...

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Bibliografiska uppgifter
I publikationen:Genome Res
Huvudupphovsmän: Shrestha, Shaleen, Sewell, Jared Allan, Santoso, Clarissa Stephanie, Forchielli, Elena, Carrasco Pro, Sebastian, Martinez, Melissa, Fuxman Bass, Juan Ignacio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2019
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Method
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724672/
https://ncbi.nlm.nih.gov/pubmed/31481462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.248823.119
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