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Discovering human transcription factor physical interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays

Identifying transcription factor (TF) binding to noncoding variants, uncharacterized DNA motifs, and repetitive genomic elements has been technically and computationally challenging. Current experimental methods, such as chromatin immunoprecipitation, generally test one TF at a time, and computation...

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書目詳細資料
發表在:Genome Res
Main Authors: Shrestha, Shaleen, Sewell, Jared Allan, Santoso, Clarissa Stephanie, Forchielli, Elena, Carrasco Pro, Sebastian, Martinez, Melissa, Fuxman Bass, Juan Ignacio
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724672/
https://ncbi.nlm.nih.gov/pubmed/31481462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.248823.119
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