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Evaluating the impact of single nucleotide variants on transcription factor binding

Diseases and phenotypes caused by disrupted transcription factor (TF) binding are being identified, but progress is hampered by our limited capacity to predict such functional alterations. Improving predictions may be dependent on expanding the set of bona fide TF binding alterations. Allele-specifi...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Shi, Wenqiang, Fornes, Oriol, Mathelier, Anthony, Wasserman, Wyeth W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137422/
https://ncbi.nlm.nih.gov/pubmed/27492288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw691
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