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Evaluating the impact of single nucleotide variants on transcription factor binding

Diseases and phenotypes caused by disrupted transcription factor (TF) binding are being identified, but progress is hampered by our limited capacity to predict such functional alterations. Improving predictions may be dependent on expanding the set of bona fide TF binding alterations. Allele-specifi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Shi, Wenqiang, Fornes, Oriol, Mathelier, Anthony, Wasserman, Wyeth W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137422/
https://ncbi.nlm.nih.gov/pubmed/27492288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw691
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