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Evaluating the impact of single nucleotide variants on transcription factor binding

Diseases and phenotypes caused by disrupted transcription factor (TF) binding are being identified, but progress is hampered by our limited capacity to predict such functional alterations. Improving predictions may be dependent on expanding the set of bona fide TF binding alterations. Allele-specifi...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Shi, Wenqiang, Fornes, Oriol, Mathelier, Anthony, Wasserman, Wyeth W.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137422/
https://ncbi.nlm.nih.gov/pubmed/27492288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw691
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