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Genome-wide segregation of single nucleotide and structural variants into single cancer cells

BACKGROUND: Single-cell genome sequencing provides high-resolution details of the clonal genomic modifications that occur during cancer initiation, progression, and ongoing evolution as patients undergo treatment. One limitation of current single-cell sequencing strategies is a suboptimal capacity t...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Easton, John, Gonzalez-Pena, Veronica, Yergeau, Donald, Ma, Xiaotu, Gawad, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702214/
https://ncbi.nlm.nih.gov/pubmed/29178827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4286-1
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