Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis

Pneumonias caused by influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity and high mortality rate. Previously, we have shown that bacterial pore-forming toxin (PFT)-mediated necroptosis is a key driver of acute lung injury during bacterial pneumonia. Her...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Gonzalez-Juarbe, Norberto, Riegler, Ashleigh N., Jureka, Alexander S., Gilley, Ryan P., Brand, Jeffrey D., Trombley, John E., Scott, Ninecia R., Platt, Maryann P., Dube, Peter H., Petit, Chad M., Harrod, Kevin S., Orihuela, Carlos J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570217/
https://ncbi.nlm.nih.gov/pubmed/32846120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108062
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