RNA-sequencing of IDH-wild-type glioblastoma with chromothripsis identifies novel gene fusions with potential oncogenic properties

Glioblastoma (GBM) is the most frequent and most aggressive form of glioma. It is characterized by marked genomic instability, which suggests that chromothripsis (CT) might be involved in GBM initiation. Recently, CT has emerged as an alternative mechanism of cancer development, involving massive ch...

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Ah-Pine, Franck, Casas, Déborah, Menei, Philippe, Boisselier, Blandine, Garcion, Emmanuel, Rousseau, Audrey
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2020
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Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569239/
https://ncbi.nlm.nih.gov/pubmed/33074125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100884
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