Detection, characterization and inhibition of FGFR-TACC fusions in IDH wild type glioma

PURPOSE: Oncogenic fusions consisting of FGFR and TACC are present in a subgroup of glioblastoma (GBM) and other human cancers and have been proposed as new therapeutic targets. We analyzed frequency, molecular features of FGFR-TACC fusions, and explored the therapeutic efficacy of inhibiting FGFR k...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Di Stefano, Anna Luisa, Fucci, Alessandra, Frattini, Veronique, Labussiere, Marianne, Mokhtari, Karima, Zoppoli, Pietro, Marie, Yannick, Bruno, Aurelie, Boisselier, Blandine, Giry, Marine, Savatovsky, Julien, Touat, Mehdi, Belaid, Hayat, Kamoun, Aurelie, Idbaih, Ahmed, Houillier, Caroline, Luo, Feng R., Soria, Jean-Charles, Tabernero, Josep, Eoli, Marica, Paterra, Rosina, Yip, Stephen, Petrecca, Kevin, Chan, Jennifer A., Finocchiaro, Gaetano, Lasorella, Anna, Sanson, Marc, Iavarone, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506218/
https://ncbi.nlm.nih.gov/pubmed/25609060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2199
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