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GENE-44. CHROMOTHRIPSIS LEADS TO CHROMOSOMAL REARRANGEMENTS AND GENE FUSIONS IN PRIMARY GLIOBLASTOMAS
BACKGROUND: Glioblastoma (GB) is the most frequent and lethal form of diffuse glioma. GB displays chromosome instability and recurrent somatic copy number alterations. Recently, chromothripsis (CT) has been identified in cancer patients. It is a cataclysmic event in which a single or a few chromosom...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692014/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.417 |
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