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RNA-sequencing of IDH-wild-type glioblastoma with chromothripsis identifies novel gene fusions with potential oncogenic properties

Glioblastoma (GBM) is the most frequent and most aggressive form of glioma. It is characterized by marked genomic instability, which suggests that chromothripsis (CT) might be involved in GBM initiation. Recently, CT has emerged as an alternative mechanism of cancer development, involving massive ch...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Ah-Pine, Franck, Casas, Déborah, Menei, Philippe, Boisselier, Blandine, Garcion, Emmanuel, Rousseau, Audrey
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569239/
https://ncbi.nlm.nih.gov/pubmed/33074125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100884
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