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RNA-sequencing of IDH-wild-type glioblastoma with chromothripsis identifies novel gene fusions with potential oncogenic properties

Glioblastoma (GBM) is the most frequent and most aggressive form of glioma. It is characterized by marked genomic instability, which suggests that chromothripsis (CT) might be involved in GBM initiation. Recently, CT has emerged as an alternative mechanism of cancer development, involving massive ch...

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Bibliografske podrobnosti
izdano v:Transl Oncol
Main Authors: Ah-Pine, Franck, Casas, Déborah, Menei, Philippe, Boisselier, Blandine, Garcion, Emmanuel, Rousseau, Audrey
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569239/
https://ncbi.nlm.nih.gov/pubmed/33074125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100884
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