Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response

Unfolded protein response (UPR) is a conserved adaptive response that tries to restore protein homeostasis after endoplasmic reticulum (ER) stress. Recent studies highlighted the role of UPR in acute leukemias and UPR targeting has been suggested as a therapeutic approach. Aberrant Notch signaling i...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Giuli, Maria Valeria, Diluvio, Giulia, Giuliani, Eugenia, Franciosa, Giulia, Di Magno, Laura, Pignataro, Maria Gemma, Tottone, Luca, Nicoletti, Carmine, Besharat, Zein Mersini, Peruzzi, Giovanna, Pelullo, Maria, Palermo, Rocco, Canettieri, Gianluca, Talora, Claudio, d’Amati, Giulia, Bellavia, Diana, Screpanti, Isabella, Checquolo, Saula
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569087/
https://ncbi.nlm.nih.gov/pubmed/33071287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00279-7
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