Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response

Unfolded protein response (UPR) is a conserved adaptive response that tries to restore protein homeostasis after endoplasmic reticulum (ER) stress. Recent studies highlighted the role of UPR in acute leukemias and UPR targeting has been suggested as a therapeutic approach. Aberrant Notch signaling i...

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Publicat a:Oncogenesis
Autors principals: Giuli, Maria Valeria, Diluvio, Giulia, Giuliani, Eugenia, Franciosa, Giulia, Di Magno, Laura, Pignataro, Maria Gemma, Tottone, Luca, Nicoletti, Carmine, Besharat, Zein Mersini, Peruzzi, Giovanna, Pelullo, Maria, Palermo, Rocco, Canettieri, Gianluca, Talora, Claudio, d’Amati, Giulia, Bellavia, Diana, Screpanti, Isabella, Checquolo, Saula
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569087/
https://ncbi.nlm.nih.gov/pubmed/33071287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00279-7
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