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Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL()()
Deregulated Notch signaling has been extensively linked to T-cell acute lymphoblastic leukemia (T-ALL). Here, we show a direct relationship between Notch3 receptor and Jagged1 ligand in human cell lines and in a mouse model of T-ALL. We provide evidence that Notch-specific ligand Jagged1 is a new No...
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| Publicado no: | Neoplasia |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Neoplasia Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309263/ https://ncbi.nlm.nih.gov/pubmed/25499214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.10.004 |
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