Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response

Unfolded protein response (UPR) is a conserved adaptive response that tries to restore protein homeostasis after endoplasmic reticulum (ER) stress. Recent studies highlighted the role of UPR in acute leukemias and UPR targeting has been suggested as a therapeutic approach. Aberrant Notch signaling i...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Principais autores: Giuli, Maria Valeria, Diluvio, Giulia, Giuliani, Eugenia, Franciosa, Giulia, Di Magno, Laura, Pignataro, Maria Gemma, Tottone, Luca, Nicoletti, Carmine, Besharat, Zein Mersini, Peruzzi, Giovanna, Pelullo, Maria, Palermo, Rocco, Canettieri, Gianluca, Talora, Claudio, d’Amati, Giulia, Bellavia, Diana, Screpanti, Isabella, Checquolo, Saula
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569087/
https://ncbi.nlm.nih.gov/pubmed/33071287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00279-7
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