Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

BACKGROUND: Self-assembly of the amyloid-β (Aβ) peptide into aggregates, from small oligomers to amyloid fibrils, is fundamentally linked with Alzheimer’s disease (AD). However, it is clear that not all forms of Aβ are equally harmful and that linking a specific aggregate to toxicity also depends on...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: De Mena, Lorena, Smith, Michael A., Martin, Jason, Dunton, Katie L., Ceballos-Diaz, Carolina, Jansen-West, Karen R., Cruz, Pedro E., Dillon, Kristy D., Rincon-Limas, Diego E., Golde, Todd E., Moore, Brenda D., Levites, Yona
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568834/
https://ncbi.nlm.nih.gov/pubmed/33069251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00698-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados