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Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly
Association of platelet factor 4 (PF4) with heparin is a first step in formation of aggregates implicated in the development of heparin-induced thrombocytopenia (HIT), a potentially fatal immune disorder affecting 1–5% of patients receiving heparin. Despite being a critically important element in HI...
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| Izdano u: | Biophys J |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567982/ https://ncbi.nlm.nih.gov/pubmed/32348723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.012 |
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