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Electrostatic forces as dominant interactions between proteins and polyanions: an ESI-MS study of fibroblast growth factor binding to heparin oligomers

The interactions between fibroblast growth factors (FGFs) and their receptors (FGFRs) are facilitated by heparan sulfate (HS) and heparin (Hp), highly sulfated biological polyelectrolytes. The molecular basis of FGF interactions with these polyelectrolytes is highly complex due to the structural het...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Minsky, Burcu Baykal, Dubin, Paul L., Kaltashov, Igor A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808462/
https://ncbi.nlm.nih.gov/pubmed/28211013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1596-0
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